Clinical Profile for Naltrexone and Alcoholism Treatment

Treatment Improvement Protocol (TIP) 28:

About the Course:

A Clinical Profile for Naltrexone and Alcoholism Treatment, TIP 28, presents current knowledge about the use of naltrexone, an opioid antagonist. This medication was initially developed to treat opiate addiction but was subsequently found to help in preventing relapse to alcohol abuse when used with traditional treatment modalities. This TIP will help clinicians and treatment providers use naltrexone safely and effectively to enhance patient care and improve treatment outcomes. This course covers Chapter 5 only.


U.S. Department of Health and Human Services

Publication Date:




About the Author:

Naltrexone and Alcoholism Treatment was published as Treatment Improvement Protocol (TIP) 28 by the Substance Abuse and Mental Health Services Administration (SAMHSA).

Recommended For:

This course is recommended for health care professionals, especially addiction counselors, psychologists, mental health counselors, social workers, and nurses who seek knowledge about a clinical profile for naltrexone and alcoholism treatment. It is appropriate for intermediate levels of participants’ knowledge.

Course Objectives:

  1. Explain the development and history of naltrexone.

  2. Describe the pharmacological properties of naltrexone.

  3. Discuss the safety of naltrexone and its common adverse effects.

Exam Questions

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